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Proteins/UNIPROT:Q9Y624
Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (By similarity). Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration. Involved in platelet activation..
(Microbial infection) Acts as a receptor for Mammalian reovirus sigma-1..
(Microbial infection) Acts as a receptor for Human Rotavirus strain Wa..
Function from UniProtKB (Q9Y624), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
28 statements
28 statements · 4 reference databases · Subject: F11R · Sources: gene ontology, Hetionet, Reactome, WikiPathways
9 names
Resolves to: F11R