Loading the page.
Proteins/UNIPROT:Q15884
Functions as an activator of the E3 ubiquitin protein ligase ITCH in the ubiquitination of the CXCL12-activated CXCR4 receptor. Thereby, triggers CXCR4 endocytosis and desensitization, negatively regulating the CXCL12/CXCR4 signaling pathway..
Function from UniProtKB (Q15884), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
9 statements
9 statements · 1 reference database · Subject: ENTREP1 · Sources: Hetionet
5 names
Resolves to: ENTREP1