Proteins/UNIPROT:O14682

ENC1

ProteinUNIPROT:O14682

Actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. Down-regulates transcription factor NF2L2/NRF2 by decreasing the rate of protein synthesis and not via a ubiquitin-mediated proteasomal degradation mechanism..

Function from UniProtKB (O14682), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

13 statements

13 statements · 3 reference databases · Subject: ENC1 · Sources: gene ontology, Hetionet, WikiPathways

Order

CUL3 interacts with ENC1ProteinHetionet hetionet:interacts:8452-8507Inferred only
HSP90AA1 interacts with ENC1ProteinHetionet hetionet:interacts:3320-8507Inferred only
HSP90AB1 interacts with ENC1ProteinHetionet hetionet:interacts:3326-8507Inferred only
ENC1 interacts with NACC1ProteinHetionet hetionet:interacts:112939-8507Inferred only
NFE2L2 interacts with ENC1ProteinHetionet hetionet:interacts:4780-8507Inferred only
RB1 interacts with ENC1ProteinHetionet hetionet:interacts:5925-8507Inferred only
SNCA interacts with ENC1ProteinHetionet hetionet:interacts:6622-8507Inferred only
TGFBR1 interacts with ENC1ProteinHetionet hetionet:interacts:7046-8507Inferred only
UBC interacts with ENC1ProteinHetionet hetionet:interacts:7316-8507Inferred only
ENC1 participates in Glucocorticoid receptor pathwayPathwayWikiPathways WP2880Inferred only
ENC1 participates in Nuclear receptors meta pathwayPathwayWikiPathways WP2882Inferred only
ENC1 regulates negative regulation of translationBiological processgene ontology O14682|GO:0017148Inferred only

Show the remaining 1

ENC1 regulates positive regulation of neuron projection developmentBiological processgene ontology O14682|GO:0010976Inferred only

Other names

7 names

Resolves to: ENC1

Also called: ENC-1Kelch-like protein 37KLHL37NRPBNuclear matrix protein NRP/Bp53-induced gene 10 proteinPIG10

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