Proteins/UNIPROT:Q8IYF1

ELOA2

ProteinUNIPROT:Q8IYF1

SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A2 is transcriptionally active but its transcription activity is not enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex)..

Function from UniProtKB (Q8IYF1), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

47 statements

47 statements · 3 reference databases · Subject: ELOA2 · Sources: gene ontology, Hetionet, Reactome

Order

CALCOCO2 interacts with ELOA2ProteinHetionet hetionet:interacts:10241-51224Inferred only
CBX5 interacts with ELOA2ProteinHetionet hetionet:interacts:23468-51224Inferred only
CDK6 interacts with ELOA2ProteinHetionet hetionet:interacts:1021-51224Inferred only
ELOA2 interacts with CEP70ProteinHetionet hetionet:interacts:51224-80321Inferred only
COIL interacts with ELOA2ProteinHetionet hetionet:interacts:51224-8161Inferred only
DVL2 interacts with ELOA2ProteinHetionet hetionet:interacts:1856-51224Inferred only
ELOB interacts with ELOA2ProteinHetionet hetionet:interacts:51224-6923Inferred only
ELOC interacts with ELOA2ProteinHetionet hetionet:interacts:51224-6921Inferred only
ELOA2 interacts with KRTAP4-12ProteinHetionet hetionet:interacts:51224-83755Inferred only
ELOA2 interacts with KXD1ProteinHetionet hetionet:interacts:51224-79036Inferred only
ELOA2 interacts with SOHLH2ProteinHetionet hetionet:interacts:51224-54937Inferred only
TRAF2 interacts with ELOA2ProteinHetionet hetionet:interacts:51224-7186Inferred only

Show the remaining 35

TRIM37 interacts with ELOA2ProteinHetionet hetionet:interacts:4591-51224Inferred only
ZBTB43 interacts with ELOA2ProteinHetionet hetionet:interacts:23099-51224Inferred only
ZNF165 interacts with ELOA2ProteinHetionet hetionet:interacts:51224-7718Inferred only
ELOA2 participates in Adaptive Immune SystemPathwayReactome R-HSA-1280218Inferred only
ELOA2 participates in Affinity selection of immunoglobulinsPathwayReactome R-HSA-9938027Inferred only
ELOA2 participates in DiseasePathwayReactome R-HSA-1643685Inferred only
ELOA2 participates in Formation of HIV elongation complex in the absence of HIV TatPathwayReactome R-HSA-167152Inferred only
ELOA2 participates in Formation of HIV-1 elongation complex containing HIV-1 TatPathwayReactome R-HSA-167200Inferred only
ELOA2 participates in Formation of RNA Pol II elongation complexPathwayReactome R-HSA-112382Inferred only
ELOA2 participates in Gene expression (Transcription)PathwayReactome R-HSA-74160Inferred only
ELOA2 participates in Generic Transcription PathwayPathwayReactome R-HSA-212436Inferred only
ELOA2 participates in HIV elongation arrest and recoveryPathwayReactome R-HSA-167287Inferred only
ELOA2 participates in HIV InfectionPathwayReactome R-HSA-162906Inferred only
ELOA2 participates in HIV Life CyclePathwayReactome R-HSA-162587Inferred only
ELOA2 participates in HIV Transcription ElongationPathwayReactome R-HSA-167169Inferred only
ELOA2 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
ELOA2 participates in Immunoglobulin maturationPathwayReactome R-HSA-9938026Inferred only
ELOA2 participates in Infectious diseasePathwayReactome R-HSA-5663205Inferred only
ELOA2 participates in Late Phase of HIV Life CyclePathwayReactome R-HSA-162599Inferred only
ELOA2 participates in Pausing and recovery of HIV elongationPathwayReactome R-HSA-167290Inferred only
ELOA2 participates in Pausing and recovery of Tat-mediated HIV elongationPathwayReactome R-HSA-167238Inferred only
ELOA2 participates in RNA Polymerase II Pre-transcription EventsPathwayReactome R-HSA-674695Inferred only
ELOA2 participates in RNA Polymerase II TranscriptionPathwayReactome R-HSA-73857Inferred only
ELOA2 participates in RNA Polymerase II Transcription ElongationPathwayReactome R-HSA-75955Inferred only
ELOA2 participates in Somatic hypermutation of immunoglobulin genesPathwayReactome R-HSA-9938024Inferred only
ELOA2 participates in Tat-mediated elongation of the HIV-1 transcriptPathwayReactome R-HSA-167246Inferred only
ELOA2 participates in Tat-mediated HIV elongation arrest and recoveryPathwayReactome R-HSA-167243Inferred only
ELOA2 participates in TP53 Regulates Transcription of DNA Repair GenesPathwayReactome R-HSA-6796648Inferred only
ELOA2 participates in Transcription of the HIV genomePathwayReactome R-HSA-167172Inferred only
ELOA2 participates in Transcriptional Regulation by TP53PathwayReactome R-HSA-3700989Inferred only
ELOA2 participates in Viral Infection PathwaysPathwayReactome R-HSA-9824446Inferred only
ELOA2 regulates regulation of DNA-templated transcription elongationBiological processgene ontology Q8IYF1|GO:0032784Inferred only
ELOA2 increases the expression of GADD45AProteinHetionet hetionet:regulates:51224-1647Inferred only
ELOA2 increases the expression of RBM6ProteinHetionet hetionet:regulates:51224-10180Inferred only
ELOA2 decreases the expression of TIMM9ProteinHetionet hetionet:regulates:51224-26520Inferred only

Other names

4 names

Resolves to: ELOA2

Also called: RNA polymerase II transcription factor SIII subunit A2TCEB3BTCEB3LTranscription elongation factor B polypeptide 3B

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