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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:P0DPD6

ECE2

Protein·UNIPROT:P0DPD6

Open in the graph

Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May play a role in amyloid-beta processing (By similarity)..

Function from UniProtKB (P0DPD6), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

9 statements

9 statements · 3 reference databases · Subject: ECE2 · Sources: Hetionet, Reactome, UniProt

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ECE2 covaries with ZNF699ProteinHetionet hetionet:covaries:374879-9718Inferred only
CASP10 interacts with ECE2ProteinHetionet hetionet:interacts:843-9718Inferred only
UBC interacts with ECE2ProteinHetionet hetionet:interacts:7316-9718Inferred only
ECE2 participates in Class A/1 (Rhodopsin-like receptors)PathwayReactome R-HSA-373076Inferred only
ECE2 participates in GPCR ligand bindingPathwayReactome R-HSA-500792Inferred only
ECE2 participates in Peptide ligand-binding receptorsPathwayReactome R-HSA-375276Inferred only
ECE2 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
ECE2 participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only
ECE2 requires the cofactor Zn(2+)CompoundUniProt P0DPD6Inferred only

Other names

2 names

Resolves to: ECE2

Also called: ECE-2KIAA0604

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