Proteins/UNIPROT:Q8NCM8

DYNC2H1

ProteinUNIPROT:Q8NCM8

May function as a motor for intraflagellar retrograde transport. Functions in cilia biogenesis. May play a role in transport between endoplasmic reticulum and Golgi or organization of the Golgi in cells (By similarity)..

Function from UniProtKB (Q8NCM8), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

3 rows

asphyxiating thoracic dystrophy 3 has a germline basis in DYNC2H1DiseaseGenCC HGNC:2962|MONDO:0013127Inferred only
Jeune syndrome has a germline basis in DYNC2H1DiseaseGenCC HGNC:2962|MONDO:0018770Inferred only
short rib-polydactyly syndrome, Majewski type has a germline basis in DYNC2H1DiseaseGenCC HGNC:2962|MONDO:0019662Inferred only

Statements

7 statements

7 statements · 1 reference database · Subject: DYNC2H1 · Sources: Reactome

Order

DYNC2H1 participates in Assembly of the 9+0 primary ciliumPathwayReactome R-HSA-9975921Inferred only
DYNC2H1 participates in Cilium AssemblyPathwayReactome R-HSA-5617833Inferred only
DYNC2H1 participates in Hedgehog 'off' statePathwayReactome R-HSA-5610787Inferred only
DYNC2H1 participates in Intraflagellar transportPathwayReactome R-HSA-5620924Inferred only
DYNC2H1 participates in Organelle biogenesis and maintenancePathwayReactome R-HSA-1852241Inferred only
DYNC2H1 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
DYNC2H1 participates in Signaling by HedgehogPathwayReactome R-HSA-5358351Inferred only

Other names

10 names

Resolves to: DYNC2H1

Also called: Cytoplasmic dynein 2 heavy chainDHC1BDHC2DNCH2DYH1BDynein cytoplasmic heavy chain 2Dynein heavy chain 11Dynein heavy chain isotype 1BhDHC11KIAA1997

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