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Proteins/UNIPROT:Q8NBA8
Catalyzes the formation of 3-(3-amino-3-carboxypropyl)uridine (acp3U) at position 20a in the D-loop of several cytoplasmic tRNAs (acp3U(20a)). Also has a weak activity to form acp3U at position 20 in the D-loop of tRNAs (acp3U(20)). Involved in glycoRNA biosynthesis by mediating formation of acp3U, which acts as an attachment site for N-glycans on tRNAs. GlycoRNAs consist of RNAs modified with secretory N-glycans that are presented on the cell surface..
Function from UniProtKB (Q8NBA8), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 statements
3 statements · 2 reference databases · Subject: DTWD2 · Sources: Hetionet, Rhea
1 reaction
a uridine in tRNA+S-adenosyl-L-methioninea 3-[(3S)-3-amino-3-carboxypropyl]uridine in tRNA+S-methyl-5'-thioadenosine+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:62432CC BY 4.0Reference data
1 name
Resolves to: DTWD2