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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:O14625

CXCL11

Protein·UNIPROT:O14625

Open in the graph

Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.

Function from UniProtKB (O14625), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

31 statements

31 statements · 4 reference databases · Subject: CXCL11 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

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CXCL11 covaries with IFITM1ProteinHetionet hetionet:covaries:6373-8519Inferred only
PCDHB10 covaries with CXCL11ProteinHetionet hetionet:covaries:56126-6373Inferred only
CXCL11 covaries with ZNF470ProteinHetionet hetionet:covaries:388566-6373Inferred only
CXCL11 covaries with ZWINTProteinHetionet hetionet:covaries:11130-6373Inferred only
CCR3 interacts with CXCL11ProteinHetionet hetionet:interacts:1232-6373Inferred only
CXCR3 interacts with CXCL11ProteinHetionet hetionet:interacts:2833-6373Inferred only
DPP4 interacts with CXCL11ProteinHetionet hetionet:interacts:1803-6373Inferred only
IRF1 interacts with CXCL11ProteinHetionet hetionet:interacts:3659-6373Inferred only
IRF2 interacts with CXCL11ProteinHetionet hetionet:interacts:3660-6373Inferred only
NFKB1 interacts with CXCL11ProteinHetionet hetionet:interacts:4790-6373Inferred only
CXCL11 participates in 2q37 copy number variation syndromePathwayWikiPathways WP5224Inferred only
CXCL11 participates in Allograft rejectionPathwayWikiPathways WP2328Inferred only

Show the remaining 19

CXCL11 participates in CAMKK2 pathwayPathwayWikiPathways WP4874Inferred only
CXCL11 participates in Chemokine receptors bind chemokinesPathwayReactome R-HSA-380108Inferred only
CXCL11 participates in Chemokine signalingPathwayWikiPathways WP3929Inferred only
CXCL11 participates in Class A/1 (Rhodopsin-like receptors)PathwayReactome R-HSA-373076Inferred only
CXCL11 participates in Cytokine cytokine receptor interactionPathwayWikiPathways WP5473Inferred only
CXCL11 participates in G alpha (i) signalling eventsPathwayReactome R-HSA-418594Inferred only
CXCL11 participates in GPCR downstream signallingPathwayReactome R-HSA-388396Inferred only
CXCL11 participates in GPCR ligand bindingPathwayReactome R-HSA-500792Inferred only
CXCL11 participates in Lung pathology of COVID 19PathwayWikiPathways WP5146Inferred only
CXCL11 participates in Overview of proinflammatory and profibrotic mediatorsPathwayWikiPathways WP5095Inferred only
CXCL11 participates in Peptide ligand-binding receptorsPathwayReactome R-HSA-375276Inferred only
CXCL11 participates in Regulation of toll like receptor signalingPathwayWikiPathways WP1449Inferred only
CXCL11 participates in SARS CoV 2 innate immunity evasion and cell specific immune responsePathwayWikiPathways WP5039Inferred only
CXCL11 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
CXCL11 participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only
CXCL11 participates in Toll like receptor signalingPathwayWikiPathways WP75Inferred only
CXCL11 participates in Uterine natural killer cells and progesterone estrogen and chorionic gonadotropinPathwayWikiPathways WP5569Inferred only
CXCL11 regulates positive regulation of release of sequestered calcium ion into cytosolBiological processgene ontology O14625|GO:0051281Inferred only
CXCL11 regulates regulation of cell population proliferationBiological processgene ontology O14625|GO:0042127Inferred only

Other names

10 names

Resolves to: CXCL11

Also called: Beta-R1H174I-TACInterferon gamma-inducible protein 9Interferon-inducible T-cell alpha chemoattractantIP-9ITACSCYB11SCYB9BSmall-inducible cytokine B11

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