Proteins/UNIPROT:Q9P2I0

CPSF2

ProteinUNIPROT:Q9P2I0

Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing..

Function from UniProtKB (Q9P2I0), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

29 statements

29 statements · 3 reference databases · Subject: CPSF2 · Sources: Hetionet, Reactome, WikiPathways

Order

CA11 covaries with CPSF2ProteinHetionet hetionet:covaries:53981-770Inferred only
OR2C3 covaries with CPSF2ProteinHetionet hetionet:covaries:53981-81472Inferred only
PRKAA1 covaries with CPSF2ProteinHetionet hetionet:covaries:53981-5562Inferred only
RPL18A covaries with CPSF2ProteinHetionet hetionet:covaries:53981-6142Inferred only
CPSF2 covaries with SSU72ProteinHetionet hetionet:covaries:29101-53981Inferred only
UBR7 covaries with CPSF2ProteinHetionet hetionet:covaries:53981-55148Inferred only
BARD1 interacts with CPSF2ProteinHetionet hetionet:interacts:53981-580Inferred only
CUL3 interacts with CPSF2ProteinHetionet hetionet:interacts:53981-8452Inferred only
POLR2A interacts with CPSF2ProteinHetionet hetionet:interacts:53981-5430Inferred only
SUMO2 interacts with CPSF2ProteinHetionet hetionet:interacts:53981-6613Inferred only
UBC interacts with CPSF2ProteinHetionet hetionet:interacts:53981-7316Inferred only
CPSF2 participates in Dengue Virus InfectionPathwayReactome R-HSA-9839923Inferred only

Show the remaining 17

CPSF2 participates in Dengue Virus-Host InteractionsPathwayReactome R-HSA-9918481Inferred only
CPSF2 participates in DiseasePathwayReactome R-HSA-1643685Inferred only
CPSF2 participates in Gene expression (Transcription)PathwayReactome R-HSA-74160Inferred only
CPSF2 participates in Infectious diseasePathwayReactome R-HSA-5663205Inferred only
CPSF2 participates in Metabolism of RNAPathwayReactome R-HSA-8953854Inferred only
CPSF2 participates in mRNA 3'-end processingPathwayReactome R-HSA-72187Inferred only
CPSF2 participates in mRNA PolyadenylationPathwayReactome R-HSA-9770562Inferred only
CPSF2 participates in mRNA processingPathwayWikiPathways WP411Inferred only
CPSF2 participates in Processing of Capped Intron-Containing Pre-mRNAPathwayReactome R-HSA-72203Inferred only
CPSF2 participates in Processing of Capped Intronless Pre-mRNAPathwayReactome R-HSA-75067Inferred only
CPSF2 participates in Processing of Intronless Pre-mRNAsPathwayReactome R-HSA-77595Inferred only
CPSF2 participates in RNA Polymerase II TranscriptionPathwayReactome R-HSA-73857Inferred only
CPSF2 participates in RNA Polymerase II Transcription TerminationPathwayReactome R-HSA-73856Inferred only
CPSF2 participates in Transport of Mature mRNA Derived from an Intronless TranscriptPathwayReactome R-HSA-159231Inferred only
CPSF2 participates in Transport of Mature mRNAs Derived from Intronless TranscriptsPathwayReactome R-HSA-159234Inferred only
CPSF2 participates in Transport of Mature Transcript to CytoplasmPathwayReactome R-HSA-72202Inferred only
CPSF2 participates in Viral Infection PathwaysPathwayReactome R-HSA-9824446Inferred only

Other names

4 names

Resolves to: CPSF2

Also called: Cleavage and polyadenylation specificity factor 100 kDa subunitCPSF 100 kDa subunitCPSF100KIAA1367

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