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Proteins/UNIPROT:Q01955
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
Tumstatin, a cleavage fragment corresponding to the collagen alpha 3(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity; these two anti-tumor properties may be regulated via RGD-independent ITGB3-mediated mechanisms.
Function from UniProtKB (Q01955), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
5 rows
44 statements
44 statements · 4 reference databases · Subject: COL4A3 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
3 names
Resolves to: COL4A3