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Proteins/UNIPROT:Q99715

COL12A1

Protein·UNIPROT:Q99715

Open in the graph

Type XII collagen interacts with type I collagen-containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix..

Function from UniProtKB (Q99715), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

4 rows

Bethlem myopathy has a germline basis in COL12A1DiseaseGenCC HGNC:2188|MONDO:0008029Inferred only
Bethlem myopathy 2 has a germline basis in COL12A1DiseaseGenCC HGNC:2188|MONDO:0034022Inferred only
Ullrich congenital muscular dystrophy has a germline basis in COL12A1DiseaseGenCC HGNC:2188|MONDO:0000355Inferred only
Ullrich congenital muscular dystrophy 2 has a germline basis in COL12A1DiseaseGenCC HGNC:2188|MONDO:0014654Inferred only

Statements

9 statements

9 statements · 2 reference databases · Subject: COL12A1 · Sources: Hetionet, Reactome

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COL12A1 interacts with DYSFProteinHetionet hetionet:interacts:1303-8291Inferred only
COL12A1 interacts with MYBPC2ProteinHetionet hetionet:interacts:1303-4606Inferred only
COL12A1 participates in Assembly of collagen fibrils and other multimeric structuresPathwayReactome R-HSA-2022090Inferred only
COL12A1 participates in Collagen biosynthesis and modifying enzymesPathwayReactome R-HSA-1650814Inferred only
COL12A1 participates in Collagen chain trimerizationPathwayReactome R-HSA-8948216Inferred only
COL12A1 participates in Collagen degradationPathwayReactome R-HSA-1442490Inferred only
COL12A1 participates in Collagen formationPathwayReactome R-HSA-1474290Inferred only
COL12A1 participates in Degradation of the extracellular matrixPathwayReactome R-HSA-1474228Inferred only
COL12A1 participates in Extracellular matrix organizationPathwayReactome R-HSA-1474244Inferred only

Other names

3 names

Resolves to: COL12A1

Also called: COL12A1LCollagen alpha-1XII

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