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Proteins/UNIPROT:Q96NY7
In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor (By similarity). Can insert into membranes and form voltage-dependent chloride-selective channels. The channel opens upon membrane depolarization at positive voltages and closes at negative membrane voltages. May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport (By similarity)..
Function from UniProtKB (Q96NY7), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
20 statements
20 statements · 4 reference databases · Subject: CLIC6 · Sources: Bgee, Hetionet, Human Protein Atlas, Rhea
1 reaction
3 names
Resolves to: CLIC6