CLECL1

Functions in mediating immune cell-cell interactions. Acts as a T-cell costimulatory molecule, enhancing anti-CD3-induced proliferation. May play a role in the interaction of dendritic cells with T-cells and the cells of the adaptive immune response. Expressed in immature dendritic cells, activates downstream signaling, incuding MAPK signaling pathway leading to an induction of the major histocompatibility complex (MHC) class II expression..

Function from UniProtKB (Q8IZS7), read 2026-09-23. CC BY 4.0.