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Proteins/UNIPROT:Q9NY25
Functions as a positive regulator of osteoclastogenesis (By similarity). Cell surface receptor that signals via TYROBP. Regulates inflammatory responses (By similarity)..
(Microbial infection) Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through the phosphorylation of TYROBP. This interaction does not result in viral entry, but stimulates pro-inflammatory cytokine release..
Function from UniProtKB (Q9NY25), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
19 statements
19 statements · 3 reference databases · Subject: CLEC5A · Sources: gene ontology, Hetionet, Reactome
5 names
Resolves to: CLEC5A