Proteins/UNIPROT:Q96RK1

CITED4

ProteinUNIPROT:Q96RK1

Acts as a transcriptional coactivator for TFAP2/AP-2. Enhances estrogen-dependent transactivation mediated by estrogen receptors. May function as an inhibitor of transactivation by HIF1A by disrupting HIF1A interaction with CREBBP. May be involved in regulation of gene expression during development and differentiation of blood cells, endothelial cells and mammary epithelial cells..

Function from UniProtKB (Q96RK1), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

20 statements

20 statements · 2 reference databases · Subject: CITED4 · Sources: Hetionet, Reactome

Order

BCL10 covaries with CITED4ProteinHetionet hetionet:covaries:163732-8915Inferred only
CCDC22 covaries with CITED4ProteinHetionet hetionet:covaries:163732-28952Inferred only
CFAP53 covaries with CITED4ProteinHetionet hetionet:covaries:163732-220136Inferred only
GRIPAP1 covaries with CITED4ProteinHetionet hetionet:covaries:163732-56850Inferred only
LGI4 covaries with CITED4ProteinHetionet hetionet:covaries:163175-163732Inferred only
MN1 covaries with CITED4ProteinHetionet hetionet:covaries:163732-4330Inferred only
TGM2 covaries with CITED4ProteinHetionet hetionet:covaries:163732-7052Inferred only
TMEM255A covaries with CITED4ProteinHetionet hetionet:covaries:163732-55026Inferred only
CITED4 covaries with ZCCHC17ProteinHetionet hetionet:covaries:163732-51538Inferred only
ZNF341 covaries with CITED4ProteinHetionet hetionet:covaries:163732-84905Inferred only
EGR1 interacts with CITED4ProteinHetionet hetionet:interacts:163732-1958Inferred only
EP300 interacts with CITED4ProteinHetionet hetionet:interacts:163732-2033Inferred only

Show the remaining 8

TFAP2A interacts with CITED4ProteinHetionet hetionet:interacts:163732-7020Inferred only
TFAP2B interacts with CITED4ProteinHetionet hetionet:interacts:163732-7021Inferred only
TFAP2C interacts with CITED4ProteinHetionet hetionet:interacts:163732-7022Inferred only
CITED4 participates in Activation of the TFAP2 (AP-2) family of transcription factorsPathwayReactome R-HSA-8866907Inferred only
CITED4 participates in Gene expression (Transcription)PathwayReactome R-HSA-74160Inferred only
CITED4 participates in Generic Transcription PathwayPathwayReactome R-HSA-212436Inferred only
CITED4 participates in RNA Polymerase II TranscriptionPathwayReactome R-HSA-73857Inferred only
CITED4 participates in Transcriptional regulation by the AP-2 (TFAP2) family of transcription factorsPathwayReactome R-HSA-8864260Inferred only

Other names

3 names

Resolves to: CITED4

Also called: MRG-2MRG2MSG1-related protein 2

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