Proteins/UNIPROT:Q9BRJ6

CHLSN

ProteinUNIPROT:Q9BRJ6

Hormone secreted from the intestine in response to cholesterol, where it acts to inhibit cholesterol synthesis in the liver and VLDL secretion,leading to a reduction in circulating cholesterol levels. Acts through binding to its receptor, GPR146..

Function from UniProtKB (Q9BRJ6), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

15 statements

15 statements · 2 reference databases · Subject: CHLSN · Sources: gene ontology, Hetionet

Order

CHLSN covaries with SNX8ProteinHetionet hetionet:covaries:29886-84310Inferred only
CHLSN covaries with TP73ProteinHetionet hetionet:covaries:7161-84310Inferred only
APP interacts with CHLSNProteinHetionet hetionet:interacts:351-84310Inferred only
CAND1 interacts with CHLSNProteinHetionet hetionet:interacts:55832-84310Inferred only
CCDC85B interacts with CHLSNProteinHetionet hetionet:interacts:11007-84310Inferred only
COPS5 interacts with CHLSNProteinHetionet hetionet:interacts:10987-84310Inferred only
CUL1 interacts with CHLSNProteinHetionet hetionet:interacts:84310-8454Inferred only
HDGF interacts with CHLSNProteinHetionet hetionet:interacts:3068-84310Inferred only
NEDD4L interacts with CHLSNProteinHetionet hetionet:interacts:23327-84310Inferred only
PAXIP1 interacts with CHLSNProteinHetionet hetionet:interacts:22976-84310Inferred only
PCLAF interacts with CHLSNProteinHetionet hetionet:interacts:84310-9768Inferred only
PRNP interacts with CHLSNProteinHetionet hetionet:interacts:5621-84310Inferred only

Show the remaining 3

SUMO2 interacts with CHLSNProteinHetionet hetionet:interacts:6613-84310Inferred only
UBC interacts with CHLSNProteinHetionet hetionet:interacts:7316-84310Inferred only
CHLSN regulates negative regulation of cholesterol biosynthetic processBiological processgene ontology Q9BRJ6|GO:0045541Inferred only

Other names

3 names

Resolves to: CHLSN

Also called: C7orf50cholesinProtein cholesin

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