Proteins/UNIPROT:P40198

CEACAM3

ProteinUNIPROT:P40198

Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis..

Function from UniProtKB (P40198), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

cystic fibrosis has a germline basis in CEACAM3DiseaseGenCC HGNC:1815|MONDO:0009061Inferred only

Statements

11 statements

11 statements · 3 reference databases · Subject: CEACAM3 · Sources: gene ontology, Hetionet, Reactome

Order

CEACAM1 interacts with CEACAM3ProteinHetionet hetionet:interacts:1084-634Inferred only
CEACAM3 interacts with CSNK1A1LProteinHetionet hetionet:interacts:1084-122011Inferred only
CEACAM3 interacts with S100A8ProteinHetionet hetionet:interacts:1084-6279Inferred only
CEACAM3 interacts with SRCProteinHetionet hetionet:interacts:1084-6714Inferred only
CEACAM3 interacts with SYKProteinHetionet hetionet:interacts:1084-6850Inferred only
CEACAM3 participates in Cell surface interactions at the vascular wallPathwayReactome R-HSA-202733Inferred only
CEACAM3 participates in HemostasisPathwayReactome R-HSA-109582Inferred only
CEACAM3 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
CEACAM3 participates in Innate Immune SystemPathwayReactome R-HSA-168249Inferred only
CEACAM3 participates in Neutrophil degranulationPathwayReactome R-HSA-6798695Inferred only
CEACAM3 regulates regulation of immune system processBiological processgene ontology P40198|GO:0002682Inferred only

Other names

6 names

Resolves to: CEACAM3

Also called: Carcinoembryonic antigen CGM1Carcinoembryonic antigen-related cell adhesion molecule 3CD antigen CD66dCD66DCEA cell adhesion molecule 3CGM1

← Every protein Find it in the graph →