Proteins/UNIPROT:Q96Q40

CDK15

ProteinUNIPROT:Q96Q40

Serine/threonine-protein kinase that acts like an antiapoptotic protein that counters TRAIL/TNFSF10-induced apoptosis by inducing phosphorylation of BIRC5 at 'Thr-34'..

Function from UniProtKB (Q96Q40), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

12 statements

12 statements · 3 reference databases · Subject: CDK15 · Sources: gene ontology, Hetionet, UniProt

Order

CDK15 covaries with BTN2A2ProteinHetionet hetionet:covaries:10385-65061Inferred only
CDK15 covaries with NPBProteinHetionet hetionet:covaries:256933-65061Inferred only
HSP90AA1 interacts with CDK15ProteinHetionet hetionet:interacts:3320-65061Inferred only
CDK15 regulates regulation of cell cycle phase transitionBiological processgene ontology Q96Q40|GO:1901987Inferred only
CDK15 decreases the expression of CDC20ProteinHetionet hetionet:regulates:65061-991Inferred only
CDK15 decreases the expression of HMG20BProteinHetionet hetionet:regulates:65061-10362Inferred only
CDK15 decreases the expression of ITGAEProteinHetionet hetionet:regulates:65061-3682Inferred only
CDK15 decreases the expression of PIN1ProteinHetionet hetionet:regulates:65061-5300Inferred only
CDK15 decreases the expression of RNF167ProteinHetionet hetionet:regulates:65061-26001Inferred only
CDK15 decreases the expression of TMSB15AProteinHetionet hetionet:regulates:65061-11013Inferred only
CDK15 increases the expression of WIF1ProteinHetionet hetionet:regulates:65061-11197Inferred only
CDK15 requires the cofactor magnesium(2+)CompoundUniProt Q96Q40Inferred only

Reactions

2 reactions

L-seryl-[protein]+ATP(4-)O-phospho-L-seryl-[protein]+ADP(3-)+hydron
Catalysed by SGK1 or CDC7 or PLK4 or STK25 or CIT or RIOK3 or MAP2K7 or CHEK1 or BCKDK or IKBKB or CASK or AURKA and 347 more alternatives
Reaction pageLeft to right

Other names

7 names

Resolves to: CDK15

Also called: ALS2CR7Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 proteinCell division protein kinase 15PFTAIRE-2PFTK2Serine/threonine-protein kinase ALS2CR7Serine/threonine-protein kinase PFTAIRE-2

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