Proteins/UNIPROT:Q04900

CD164

ProteinUNIPROT:Q04900

Sialomucin that may play a key role in hematopoiesis by facilitating the adhesion of CD34(+) cells to the stroma and by negatively regulating CD34(+)CD38(lo/-) cell proliferation. Modulates the migration of umbilical cord blood CD133+ cells and this is mediated through the CXCL12/CXCR4 axis. May play an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Promotes myogenesis by enhancing CXCR4-dependent cell motility. Positively regulates myoblast migration and promotes myoblast fusion into myotubes (By similarity)..

Function from UniProtKB (Q04900), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

autosomal dominant nonsyndromic hearing loss has a germline basis in CD164DiseaseGenCC HGNC:1632|MONDO:0019587Inferred only

Statements

10 statements

10 statements · 3 reference databases · Subject: CD164 · Sources: gene ontology, Hetionet, WikiPathways

Order

CD164 interacts with ANKRD28ProteinHetionet hetionet:interacts:23243-8763Inferred only
CXCR4 interacts with CD164ProteinHetionet hetionet:interacts:7852-8763Inferred only
EGR1 interacts with CD164ProteinHetionet hetionet:interacts:1958-8763Inferred only
GRB2 interacts with CD164ProteinHetionet hetionet:interacts:2885-8763Inferred only
CD164 participates in miR targeted genes in leukocytesPathwayWikiPathways WP2003Inferred only
CD164 participates in miR targeted genes in lymphocytesPathwayWikiPathways WP2004Inferred only
CD164 participates in miR targeted genes in muscle cellPathwayWikiPathways WP2005Inferred only
CD164 regulates negative regulation of cell adhesionBiological processgene ontology Q04900|GO:0007162Inferred only
HADH decreases the expression of CD164ProteinHetionet hetionet:regulates:3033-8763Inferred only
SLC35A1 decreases the expression of CD164ProteinHetionet hetionet:regulates:10559-8763Inferred only

Other names

6 names

Resolves to: CD164

Also called: CD antigen CD164EndolynMGC-24MGC-24vMUC-24Multi-glycosylated core protein 24

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