Proteins/UNIPROT:Q99616

CCL13

ProteinUNIPROT:Q99616

Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens.

Function from UniProtKB (Q99616), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

26 statements

26 statements · 4 reference databases · Subject: CCL13 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

CCL13 covaries with ANGPTL5ProteinHetionet hetionet:covaries:253935-6357Inferred only
TNFSF10 covaries with CCL13ProteinHetionet hetionet:covaries:6357-8743Inferred only
ACKR2 interacts with CCL13ProteinHetionet hetionet:interacts:1238-6357Inferred only
CCL13 interacts with ACKR4ProteinHetionet hetionet:interacts:51554-6357Inferred only
APP interacts with CCL13ProteinHetionet hetionet:interacts:351-6357Inferred only
CCL2 interacts with CCL13ProteinHetionet hetionet:interacts:6347-6357Inferred only
CCL13 interacts with CCR2ProteinHetionet hetionet:interacts:6357-729230Inferred only
CCR3 interacts with CCL13ProteinHetionet hetionet:interacts:1232-6357Inferred only
CCR5 interacts with CCL13ProteinHetionet hetionet:interacts:1234-6357Inferred only
CXCR3 interacts with CCL13ProteinHetionet hetionet:interacts:2833-6357Inferred only
HNRNPH3 interacts with CCL13ProteinHetionet hetionet:interacts:3189-6357Inferred only
MMP1 interacts with CCL13ProteinHetionet hetionet:interacts:4312-6357Inferred only

Show the remaining 14

MMP3 interacts with CCL13ProteinHetionet hetionet:interacts:4314-6357Inferred only
CCL13 participates in 17q12 copy number variation syndromePathwayWikiPathways WP5287Inferred only
CCL13 participates in Chemokine receptors bind chemokinesPathwayReactome R-HSA-380108Inferred only
CCL13 participates in Class A/1 (Rhodopsin-like receptors)PathwayReactome R-HSA-373076Inferred only
CCL13 participates in Cytokine cytokine receptor interactionPathwayWikiPathways WP5473Inferred only
CCL13 participates in G alpha (i) signalling eventsPathwayReactome R-HSA-418594Inferred only
CCL13 participates in GPCR downstream signallingPathwayReactome R-HSA-388396Inferred only
CCL13 participates in GPCR ligand bindingPathwayReactome R-HSA-500792Inferred only
CCL13 participates in Overview of proinflammatory and profibrotic mediatorsPathwayWikiPathways WP5095Inferred only
CCL13 participates in Peptide ligand-binding receptorsPathwayReactome R-HSA-375276Inferred only
CCL13 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
CCL13 participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only
CCL13 regulates positive regulation of cell migrationBiological processgene ontology Q99616|GO:0030335Inferred only
CCL13 regulates regulation of cell shapeBiological processgene ontology Q99616|GO:0008360Inferred only

Other names

9 names

Resolves to: CCL13

Also called: CK-beta-10MCP-4MCP4Monocyte chemoattractant protein 4Monocyte chemotactic protein 4NCC-1NCC1SCYA13Small-inducible cytokine A13

← Every protein Find it in the graph →