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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:A6NHC0

CAPN8

Protein·UNIPROT:A6NHC0

Open in the graph

Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta-subunit of coatomer complex (By similarity)..

Function from UniProtKB (A6NHC0), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

5 statements

5 statements · 3 reference databases · Subject: CAPN8 · Sources: Hetionet, Reactome, UniProt

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CAPN8 covaries with DUSP10ProteinHetionet hetionet:covaries:11221-388743Inferred only
CAPN8 covaries with MS4A10ProteinHetionet hetionet:covaries:341116-388743Inferred only
CAPN8 participates in Degradation of the extracellular matrixPathwayReactome R-HSA-1474228Inferred only
CAPN8 participates in Extracellular matrix organizationPathwayReactome R-HSA-1474244Inferred only
CAPN8 requires the cofactor Ca(2+)CompoundUniProt A6NHC0Inferred only

Other names

4 names

Resolves to: CAPN8

Also called: nCL-2NCL2New calpain 2Stomach-specific M-type calpain

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