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Reference

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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:Q8N1M1

BEST3

Protein·UNIPROT:Q8N1M1Bestrophin-3

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Ligand-gated anion channel that allows the movement of chloride monoatomic anions across cell membranes when activated by calcium (Ca2+)..

Function from UniProtKB (Q8N1M1), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

6 statements

6 statements · 3 reference databases · Subject: BEST3 · Sources: Bgee, Reactome, Rhea

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BEST3 is expressed in gastrocnemiusAnatomyBgee ENSG00000127325Inferred only
BEST3 is expressed in tibialis anteriorAnatomyBgee ENSG00000127325Inferred only
BEST3 participates in Ion channel transportPathwayReactome R-HSA-983712Inferred only
BEST3 participates in Stimuli-sensing channelsPathwayReactome R-HSA-2672351Inferred only
BEST3 participates in Transport of small moleculesPathwayReactome R-HSA-382551Inferred only
chloride is transported by BEST3CompoundRhea RHEA:29823Inferred only

Reactions

1 reaction

chloridechloride
Transported by GABRR3 or GPHRA or KCNK1 or CLIC1 or GABRP or CLDN4 or GABRD or CLIC2 or SLC26A4 or GLRA3 or BEST1 or KCNK2 and 69 more alternatives
Reaction pageRight to leftBalanced
Rhea RHEA:29823CC BY 4.0Reference data

Other names

3 names

Resolves to: BEST3

Also called: Bestrophin-3Vitelliform macular dystrophy 2-like protein 3VMD2L3

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