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Proteins/UNIPROT:Q8TAM1

BBS10

Protein·UNIPROT:Q8TAM1

Open in the graph

Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis. Plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation..

Function from UniProtKB (Q8TAM1), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

3 rows

Bardet-Biedl syndrome has a germline basis in BBS10DiseaseGenCC HGNC:26291|MONDO:0015229Inferred only
Bardet-Biedl syndrome 10 has a germline basis in BBS10DiseaseGenCC HGNC:26291|MONDO:0014438Inferred only
BBS10-related ciliopathy has a germline basis in BBS10DiseaseGenCC HGNC:26291|MONDO:0700237Inferred only

Statements

24 statements

24 statements · 4 reference databases · Subject: BBS10 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

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CEP295 covaries with BBS10ProteinHetionet hetionet:covaries:79738-85459Inferred only
BBS10 interacts with BBS12ProteinHetionet hetionet:interacts:166379-79738Inferred only
CSNK1E interacts with BBS10ProteinHetionet hetionet:interacts:1454-79738Inferred only
FRZB interacts with BBS10ProteinHetionet hetionet:interacts:2487-79738Inferred only
HDAC6 interacts with BBS10ProteinHetionet hetionet:interacts:10013-79738Inferred only
MAP3K7 interacts with BBS10ProteinHetionet hetionet:interacts:6885-79738Inferred only
MAPK6 interacts with BBS10ProteinHetionet hetionet:interacts:5597-79738Inferred only
MAPK8IP2 interacts with BBS10ProteinHetionet hetionet:interacts:23542-79738Inferred only
NR4A1 interacts with BBS10ProteinHetionet hetionet:interacts:3164-79738Inferred only
PTK2 interacts with BBS10ProteinHetionet hetionet:interacts:5747-79738Inferred only
RASA1 interacts with BBS10ProteinHetionet hetionet:interacts:5921-79738Inferred only
RGS2 interacts with BBS10ProteinHetionet hetionet:interacts:5997-79738Inferred only

Show the remaining 12

TNFSF11 interacts with BBS10ProteinHetionet hetionet:interacts:79738-8600Inferred only
UBC interacts with BBS10ProteinHetionet hetionet:interacts:7316-79738Inferred only
YAE1 interacts with BBS10ProteinHetionet hetionet:interacts:57002-79738Inferred only
BBS10 participates in Assembly of the 9+0 primary ciliumPathwayReactome R-HSA-9975921Inferred only
BBS10 participates in Bardet Biedl syndromePathwayWikiPathways WP5234Inferred only
BBS10 participates in BBSome-mediated cargo-targeting to ciliumPathwayReactome R-HSA-5620922Inferred only
BBS10 participates in Cargo trafficking to the periciliary membranePathwayReactome R-HSA-5620920Inferred only
BBS10 participates in CiliopathiesPathwayWikiPathways WP4803Inferred only
BBS10 participates in Cilium AssemblyPathwayReactome R-HSA-5617833Inferred only
BBS10 participates in Genes related to primary cilium development based on CRISPR PathwayWikiPathways WP4536Inferred only
BBS10 participates in Organelle biogenesis and maintenancePathwayReactome R-HSA-1852241Inferred only
BBS10 regulates regulation of protein-containing complex assemblyBiological processgene ontology Q8TAM1|GO:0043254Inferred only

Other names

3 names

Resolves to: BBS10

Also called: Bardet-Biedl syndrome 10 proteinBBSome complex assembly protein BBS10C12orf58

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