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Proteins/UNIPROT:P47901

AVPR1B

Protein·UNIPROT:P47901

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Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

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(Microbial infection) During SARS coronavirus-2/SARS-CoV-2 infection, may recognize and internalize the complex formed by AVP/Arg-vasopressin, SARS-CoV-2 spike protein and secreted ACE2 through DNM2/dynamin 2-dependent endocytosis..

Function from UniProtKB (P47901), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

24 statements

24 statements · 4 reference databases · Subject: AVPR1B · Sources: gene ontology, Hetionet, Reactome, WikiPathways

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AVP interacts with AVPR1BProteinHetionet hetionet:interacts:551-553Inferred only
AVPR1B interacts with GRK5ProteinHetionet hetionet:interacts:2869-553Inferred only
AVPR1B participates in Class A/1 (Rhodopsin-like receptors)PathwayReactome R-HSA-373076Inferred only
AVPR1B participates in Defective AVP does not bind AVPR1A,B and causes neurohypophyseal diabetes insipidus (NDI)PathwayReactome R-HSA-5619099Inferred only
AVPR1B participates in DiseasePathwayReactome R-HSA-1643685Inferred only
AVPR1B participates in Disorders of transmembrane transportersPathwayReactome R-HSA-5619115Inferred only
AVPR1B participates in G alpha (q) signalling eventsPathwayReactome R-HSA-416476Inferred only
AVPR1B participates in GPCR downstream signallingPathwayReactome R-HSA-388396Inferred only
AVPR1B participates in GPCR ligand bindingPathwayReactome R-HSA-500792Inferred only
AVPR1B participates in GPCRs class A rhodopsin likePathwayWikiPathways WP455Inferred only
AVPR1B participates in Peptide GPCRsPathwayWikiPathways WP24Inferred only
AVPR1B participates in Peptide ligand-binding receptorsPathwayReactome R-HSA-375276Inferred only

Show the remaining 12

AVPR1B participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
AVPR1B participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only
AVPR1B participates in SLC transporter disordersPathwayReactome R-HSA-5619102Inferred only
AVPR1B participates in Soluble ACE2 mediated cell entry of SARS CoV 2PathwayWikiPathways WP5076Inferred only
AVPR1B participates in Vasopressin-like receptorsPathwayReactome R-HSA-388479Inferred only
AVPR1B regulates positive regulation of arachidonate secretionBiological processgene ontology P47901|GO:0090238Inferred only
AVPR1B regulates positive regulation of cytosolic calcium ion concentrationBiological processgene ontology P47901|GO:0007204Inferred only
AVPR1B regulates positive regulation of inositol phosphate biosynthetic processBiological processgene ontology P47901|GO:0060732Inferred only
AVPR1B regulates positive regulation of MAPK cascadeBiological processgene ontology P47901|GO:0043410Inferred only
AVPR1B regulates positive regulation of vasoconstrictionBiological processgene ontology P47901|GO:0045907Inferred only
AVPR1B regulates regulation of cell population proliferationBiological processgene ontology P47901|GO:0042127Inferred only
AVPR1B regulates regulation of systemic arterial blood pressure by vasopressinBiological processgene ontology P47901|GO:0001992Inferred only

Other names

7 names

Resolves to: AVPR1B

Also called: Antidiuretic hormone receptor 1bAVPR V1bAVPR V3AVPR3V1bRVasopressin V3 receptorVPR3

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