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Proteins/UNIPROT:Q8TF62

ATP8B4

Protein·UNIPROT:Q8TF62

Open in the graph

Component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation also seems to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable)..

Function from UniProtKB (Q8TF62), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

9 statements

9 statements · 3 reference databases · Subject: ATP8B4 · Sources: Hetionet, Reactome, UniProt

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GPR4 covaries with ATP8B4ProteinHetionet hetionet:covaries:2828-79895Inferred only
ZSWIM4 covaries with ATP8B4ProteinHetionet hetionet:covaries:65249-79895Inferred only
ATP8B4 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
ATP8B4 participates in Innate Immune SystemPathwayReactome R-HSA-168249Inferred only
ATP8B4 participates in Ion channel transportPathwayReactome R-HSA-983712Inferred only
ATP8B4 participates in Ion transport by P-type ATPasesPathwayReactome R-HSA-936837Inferred only
ATP8B4 participates in Neutrophil degranulationPathwayReactome R-HSA-6798695Inferred only
ATP8B4 participates in Transport of small moleculesPathwayReactome R-HSA-382551Inferred only
ATP8B4 requires the cofactor magnesium(2+)CompoundUniProt Q8TF62Inferred only

Other names

3 names

Resolves to: ATP8B4

Also called: ATPase class I type 8B member 4KIAA1939P4-ATPase flippase complex alpha subunit ATP8B4

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