Proteins/UNIPROT:Q02410

APBA1

ProteinUNIPROT:Q02410

Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta. Component of the LIN-10-LIN-2-LIN-7 complex, which associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules (By similarity)..

Function from UniProtKB (Q02410), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

21 statements

21 statements · 2 reference databases · Subject: APBA1 · Sources: Hetionet, Reactome

Order

APBA1 interacts with APBB1ProteinHetionet hetionet:interacts:320-322Inferred only
APBA1 interacts with APPProteinHetionet hetionet:interacts:320-351Inferred only
APBA1 interacts with CACNA1BProteinHetionet hetionet:interacts:320-774Inferred only
APBA1 interacts with CASKProteinHetionet hetionet:interacts:320-8573Inferred only
APBA1 interacts with CCSProteinHetionet hetionet:interacts:320-9973Inferred only
APBA1 interacts with CNTNAP3ProteinHetionet hetionet:interacts:320-79937Inferred only
APBA1 interacts with CNTNAP4ProteinHetionet hetionet:interacts:320-85445Inferred only
APBA1 interacts with HTR2CProteinHetionet hetionet:interacts:320-3358Inferred only
APBA1 interacts with LIN7AProteinHetionet hetionet:interacts:320-8825Inferred only
APBA1 interacts with LIN7BProteinHetionet hetionet:interacts:320-64130Inferred only
APBA1 interacts with LIN7CProteinHetionet hetionet:interacts:320-55327Inferred only
APBA1 interacts with PSEN1ProteinHetionet hetionet:interacts:320-5663Inferred only

Show the remaining 9

APBA1 participates in Activation of NMDA receptors and postsynaptic eventsPathwayReactome R-HSA-442755Inferred only
APBA1 participates in Assembly and cell surface presentation of NMDA receptorsPathwayReactome R-HSA-9609736Inferred only
APBA1 participates in Dopamine Neurotransmitter Release CyclePathwayReactome R-HSA-212676Inferred only
APBA1 participates in Neurexins and neuroliginsPathwayReactome R-HSA-6794361Inferred only
APBA1 participates in Neuronal SystemPathwayReactome R-HSA-112316Inferred only
APBA1 participates in Neurotransmitter receptors and postsynaptic signal transmissionPathwayReactome R-HSA-112314Inferred only
APBA1 participates in Neurotransmitter release cyclePathwayReactome R-HSA-112310Inferred only
APBA1 participates in Protein-protein interactions at synapsesPathwayReactome R-HSA-6794362Inferred only
APBA1 participates in Transmission across Chemical SynapsesPathwayReactome R-HSA-112315Inferred only

Other names

6 names

Resolves to: APBA1

Also called: Adapter protein X11alphaMint-1MINT1Neuron-specific X11 proteinNeuronal Munc18-1-interacting protein 1X11

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