Proteins/UNIPROT:Q6RW13

AGTRAP

ProteinUNIPROT:Q6RW13

Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation. Also induces a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity..

Function from UniProtKB (Q6RW13), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

21 statements

21 statements · 3 reference databases · Subject: AGTRAP · Sources: gene ontology, Hetionet, Reactome

Order

LCE2C covaries with AGTRAPProteinHetionet hetionet:covaries:353140-57085Inferred only
AGTR1 interacts with AGTRAPProteinHetionet hetionet:interacts:185-57085Inferred only
AGTR2 interacts with AGTRAPProteinHetionet hetionet:interacts:186-57085Inferred only
ARFIP2 interacts with AGTRAPProteinHetionet hetionet:interacts:23647-57085Inferred only
ARHGAP1 interacts with AGTRAPProteinHetionet hetionet:interacts:392-57085Inferred only
ECPAS interacts with AGTRAPProteinHetionet hetionet:interacts:23392-57085Inferred only
GPRASP1 interacts with AGTRAPProteinHetionet hetionet:interacts:57085-9737Inferred only
PBX3 interacts with AGTRAPProteinHetionet hetionet:interacts:5090-57085Inferred only
PDHX interacts with AGTRAPProteinHetionet hetionet:interacts:57085-8050Inferred only
PITPNC1 interacts with AGTRAPProteinHetionet hetionet:interacts:26207-57085Inferred only
PTPN9 interacts with AGTRAPProteinHetionet hetionet:interacts:57085-5780Inferred only
RACK1 interacts with AGTRAPProteinHetionet hetionet:interacts:10399-57085Inferred only

Show the remaining 9

SPG21 interacts with AGTRAPProteinHetionet hetionet:interacts:51324-57085Inferred only
AGTRAP interacts with TMEM14BProteinHetionet hetionet:interacts:57085-81853Inferred only
UBC interacts with AGTRAPProteinHetionet hetionet:interacts:57085-7316Inferred only
UBE2I interacts with AGTRAPProteinHetionet hetionet:interacts:57085-7329Inferred only
AGTRAP participates in DiseasePathwayReactome R-HSA-1643685Inferred only
AGTRAP participates in Diseases of signal transduction by growth factor receptors and second messengersPathwayReactome R-HSA-5663202Inferred only
AGTRAP participates in Oncogenic MAPK signalingPathwayReactome R-HSA-6802957Inferred only
AGTRAP participates in Signaling by BRAF and RAF1 fusionsPathwayReactome R-HSA-6802952Inferred only
AGTRAP regulates regulation of blood pressureBiological processgene ontology Q6RW13|GO:0008217Inferred only

Other names

3 names

Resolves to: AGTRAP

Also called: AT1 receptor-associated proteinATRAPType-1 angiotensin II receptor-associated protein

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