Biological process
negative regulation of MAPK cascade
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade.
Definition from the Gene Ontology (GO:0043409), read 2026-09-23. CC BY 4.0.
GO:0043409Gene Ontology
What the reference databases state
Statements
45 statements
45 statements · 1 reference database · Subject: negative regulation of MAPK cascade · Sources: gene ontology
- ABCA7 regulates negative regulation of MAPK cascadeProteingene ontology Q8IZY2|GO:0043409Inferred only
- APOE regulates negative regulation of MAPK cascadeProteingene ontology P02649|GO:0043409Inferred only
- CAV1 regulates negative regulation of MAPK cascadeProteingene ontology Q03135|GO:0043409Inferred only
- CAV3 regulates negative regulation of MAPK cascadeProteingene ontology P56539|GO:0043409Inferred only
- CBLC regulates negative regulation of MAPK cascadeProteingene ontology Q9ULV8|GO:0043409Inferred only
- CDK12 regulates negative regulation of MAPK cascadeProteingene ontology Q9NYV4|GO:0043409Inferred only
- DAB2IP regulates negative regulation of MAPK cascadeProteingene ontology Q5VWQ8|GO:0043409Inferred only
- DAG1 regulates negative regulation of MAPK cascadeProteingene ontology Q14118|GO:0043409Inferred only
- DUSP1 regulates negative regulation of MAPK cascadeProteingene ontology P28562|GO:0043409Inferred only
- DUSP16 regulates negative regulation of MAPK cascadeProteingene ontology Q9BY84|GO:0043409Inferred only
- DUSP26 regulates negative regulation of MAPK cascadeProteingene ontology Q9BV47|GO:0043409Inferred only
- DUSP29 regulates negative regulation of MAPK cascadeProteingene ontology Q68J44|GO:0043409Inferred only
Show the remaining 33
- DUSP3 regulates negative regulation of MAPK cascadeProteingene ontology P51452|GO:0043409Inferred only
- DUSP6 regulates negative regulation of MAPK cascadeProteingene ontology Q16828|GO:0043409Inferred only
- GBA1 regulates negative regulation of MAPK cascadeProteingene ontology P04062|GO:0043409Inferred only
- GSTP1 regulates negative regulation of MAPK cascadeProteingene ontology P09211|GO:0043409Inferred only
- IGF1R regulates negative regulation of MAPK cascadeProteingene ontology P08069|GO:0043409Inferred only
- IL1B regulates negative regulation of MAPK cascadeProteingene ontology P01584|GO:0043409Inferred only
- IRAK3 regulates negative regulation of MAPK cascadeProteingene ontology Q9Y616|GO:0043409Inferred only
- LAX1 regulates negative regulation of MAPK cascadeProteingene ontology Q8IWV1|GO:0043409Inferred only
- LILRB4 regulates negative regulation of MAPK cascadeProteingene ontology Q8NHJ6|GO:0043409Inferred only
- NF1 regulates negative regulation of MAPK cascadeProteingene ontology P21359|GO:0043409Inferred only
- P2RX7 regulates negative regulation of MAPK cascadeProteingene ontology Q99572|GO:0043409Inferred only
- PEBP1 regulates negative regulation of MAPK cascadeProteingene ontology P30086|GO:0043409Inferred only
- PIK3CB regulates negative regulation of MAPK cascadeProteingene ontology P42338|GO:0043409Inferred only
- PIK3R2 regulates negative regulation of MAPK cascadeProteingene ontology O00459|GO:0043409Inferred only
- PP2D1 regulates negative regulation of MAPK cascadeProteingene ontology A8MPX8|GO:0043409Inferred only
- PPARG regulates negative regulation of MAPK cascadeProteingene ontology P37231|GO:0043409Inferred only
- PPEF2 regulates negative regulation of MAPK cascadeProteingene ontology O14830|GO:0043409Inferred only
- PPP5C regulates negative regulation of MAPK cascadeProteingene ontology P53041|GO:0043409Inferred only
- PRDM15 regulates negative regulation of MAPK cascadeProteingene ontology P57071|GO:0043409Inferred only
- PRKCD regulates negative regulation of MAPK cascadeProteingene ontology Q05655|GO:0043409Inferred only
- PSMD10 regulates negative regulation of MAPK cascadeProteingene ontology O75832|GO:0043409Inferred only
- RASGRF1 regulates negative regulation of MAPK cascadeProteingene ontology Q13972|GO:0043409Inferred only
- SBNO1 regulates negative regulation of MAPK cascadeProteingene ontology A3KN83|GO:0043409Inferred only
- SH2B3 regulates negative regulation of MAPK cascadeProteingene ontology Q9UQQ2|GO:0043409Inferred only
- SH3GL2 regulates negative regulation of MAPK cascadeProteingene ontology Q99962|GO:0043409Inferred only
- SMPD1 regulates negative regulation of MAPK cascadeProteingene ontology P17405|GO:0043409Inferred only
- SPRED1 regulates negative regulation of MAPK cascadeProteingene ontology Q7Z699|GO:0043409Inferred only
- SPRED2 regulates negative regulation of MAPK cascadeProteingene ontology Q7Z698|GO:0043409Inferred only
- SPRY3 regulates negative regulation of MAPK cascadeProteingene ontology O43610|GO:0043409Inferred only
- STYXL2 regulates negative regulation of MAPK cascadeProteingene ontology Q5VZP5|GO:0043409Inferred only
- TRIB1 regulates negative regulation of MAPK cascadeProteingene ontology Q96RU8|GO:0043409Inferred only
- TRIB3 regulates negative regulation of MAPK cascadeProteingene ontology Q96RU7|GO:0043409Inferred only
- UCHL1 regulates negative regulation of MAPK cascadeProteingene ontology P09936|GO:0043409Inferred only