Pathway
Zinc influx into cells by the SLC39 gene family
The SLC39 gene family encode zinc transporters belonging to the ZIP (Zrt-, Irt-like proteins) family of metal ion transporters. All ZIPs transport metal ions into the cytoplasm of cells, be it across cellular membranes or from intracellular compartments. To date, there are 14 human SLC39 genes that encode the zinc transporters hZIP1-14. There are 9 members which belong to a subfamily of the ZIPs called the LZTs (LIV-1 subfamily of ZIP zinc transporters) (Taylor KM and Nicholson RI, 2003). Of these 14 proteins, four (hZIP9, 11, 12 and 13) have no function determined yet (Eide DJ, 2004).
REACT:R-HSA-442380Reactome
What the reference databases state
Statements
10 statements
10 statements · 1 reference database · Subject: Zinc influx into cells by the SLC39 gene family · Sources: Reactome
- SLC39A1 participates in Zinc influx into cells by the SLC39 gene familyProteinReactome R-HSA-442380Inferred only
- SLC39A10 participates in Zinc influx into cells by the SLC39 gene familyProteinReactome R-HSA-442380Inferred only
- SLC39A14 participates in Zinc influx into cells by the SLC39 gene familyProteinReactome R-HSA-442380Inferred only
- SLC39A2 participates in Zinc influx into cells by the SLC39 gene familyProteinReactome R-HSA-442380Inferred only
- SLC39A3 participates in Zinc influx into cells by the SLC39 gene familyProteinReactome R-HSA-442380Inferred only
- SLC39A4 participates in Zinc influx into cells by the SLC39 gene familyProteinReactome R-HSA-442380Inferred only
- SLC39A5 participates in Zinc influx into cells by the SLC39 gene familyProteinReactome R-HSA-442380Inferred only
- SLC39A6 participates in Zinc influx into cells by the SLC39 gene familyProteinReactome R-HSA-442380Inferred only
- SLC39A7 participates in Zinc influx into cells by the SLC39 gene familyProteinReactome R-HSA-442380Inferred only
- SLC39A8 participates in Zinc influx into cells by the SLC39 gene familyProteinReactome R-HSA-442380Inferred only