Pathway
Synthesis of GDP-mannose
GDP-mannose is the mannose donor for the first 5 mannose addition reactions in the N-glycan precursor synthesis, and also for the synthesis of Dolichyl-phosphate-mannose involved in other mannose transfer reactions. It is synthesized from fructose 6-phosphate and GTP in three steps.
REACT:R-HSA-446205Reactome
What the reference databases state
Statements
6 statements
6 statements · 1 reference database · Subject: Synthesis of GDP-mannose · Sources: Reactome
- GMPPA participates in Synthesis of GDP-mannoseProteinReactome R-HSA-446205Inferred only
- GMPPB participates in Synthesis of GDP-mannoseProteinReactome R-HSA-446205Inferred only
- HK1 participates in Synthesis of GDP-mannoseProteinReactome R-HSA-446205Inferred only
- MPI participates in Synthesis of GDP-mannoseProteinReactome R-HSA-446205Inferred only
- PMM1 participates in Synthesis of GDP-mannoseProteinReactome R-HSA-446205Inferred only
- PMM2 participates in Synthesis of GDP-mannoseProteinReactome R-HSA-446205Inferred only