Pathway
p75NTR signals via NF-kB
The NF-kB pathway is an important pro-survival signalling pathway activated by mature NGF, but not BDNF or NT-3, through p75NTR. It is unclear whether TRKA activity also affects NF-kB activation.
REACT:R-HSA-193639Reactome
What the reference databases state
Statements
16 statements
16 statements · 1 reference database · Subject: p75NTR signals via NF-kB · Sources: Reactome
- IKBKB participates in p75NTR signals via NF-kBProteinReactome R-HSA-193639Inferred only
- IRAK1 participates in p75NTR signals via NF-kBProteinReactome R-HSA-193639Inferred only
- MYD88 participates in p75NTR signals via NF-kBProteinReactome R-HSA-193639Inferred only
- NFKB1 participates in p75NTR signals via NF-kBProteinReactome R-HSA-193639Inferred only
- NFKBIA participates in p75NTR signals via NF-kBProteinReactome R-HSA-193639Inferred only
- NGF participates in p75NTR signals via NF-kBProteinReactome R-HSA-193639Inferred only
- NGFR participates in p75NTR signals via NF-kBProteinReactome R-HSA-193639Inferred only
- PRKCI participates in p75NTR signals via NF-kBProteinReactome R-HSA-193639Inferred only
- RELA participates in p75NTR signals via NF-kBProteinReactome R-HSA-193639Inferred only
- RIPK2 participates in p75NTR signals via NF-kBProteinReactome R-HSA-193639Inferred only
- RPS27A participates in p75NTR signals via NF-kBProteinReactome R-HSA-193639Inferred only
- SQSTM1 participates in p75NTR signals via NF-kBProteinReactome R-HSA-193639Inferred only
Show the remaining 4
- TRAF6 participates in p75NTR signals via NF-kBProteinReactome R-HSA-193639Inferred only
- UBA52 participates in p75NTR signals via NF-kBProteinReactome R-HSA-193639Inferred only
- UBB participates in p75NTR signals via NF-kBProteinReactome R-HSA-193639Inferred only
- UBC participates in p75NTR signals via NF-kBProteinReactome R-HSA-193639Inferred only