Pathway
Long-term potentiation
In long-term potentiation (LTP), involved in learning and memory, a brief period of synaptic activity induces a lasting increase in the strength of the synapse. LTP is initiated by NMDA receptor-mediated activation of calcium/calmodulin-dependent protein kinase II (CaMKII), followed by binding of CaMKII to the NMDA receptor and CaMKII-mediated phosphorylation of AMPA receptor subunits (reviewed by Lisman et al. 2012 and Luscher and Malenka 2012).
REACT:R-HSA-9620244Reactome
What the reference databases state
Statements
22 statements
22 statements · 1 reference database · Subject: Long-term potentiation · Sources: Reactome
- ACTN2 participates in Long-term potentiationProteinReactome R-HSA-9620244Inferred only
- CALM1 participates in Long-term potentiationProteinReactome R-HSA-9620244Inferred only
- CAMK2A participates in Long-term potentiationProteinReactome R-HSA-9620244Inferred only
- CAMK2B participates in Long-term potentiationProteinReactome R-HSA-9620244Inferred only
- CAMK2D participates in Long-term potentiationProteinReactome R-HSA-9620244Inferred only
- CAMK2G participates in Long-term potentiationProteinReactome R-HSA-9620244Inferred only
- DLG1 participates in Long-term potentiationProteinReactome R-HSA-9620244Inferred only
- DLG2 participates in Long-term potentiationProteinReactome R-HSA-9620244Inferred only
- DLG3 participates in Long-term potentiationProteinReactome R-HSA-9620244Inferred only
- DLG4 participates in Long-term potentiationProteinReactome R-HSA-9620244Inferred only
- GRIA1 participates in Long-term potentiationProteinReactome R-HSA-9620244Inferred only
- GRIA2 participates in Long-term potentiationProteinReactome R-HSA-9620244Inferred only
Show the remaining 10
- GRIN1 participates in Long-term potentiationProteinReactome R-HSA-9620244Inferred only
- GRIN2A participates in Long-term potentiationProteinReactome R-HSA-9620244Inferred only
- GRIN2B participates in Long-term potentiationProteinReactome R-HSA-9620244Inferred only
- GRIN2C participates in Long-term potentiationProteinReactome R-HSA-9620244Inferred only
- GRIN2D participates in Long-term potentiationProteinReactome R-HSA-9620244Inferred only
- LRRC7 participates in Long-term potentiationProteinReactome R-HSA-9620244Inferred only
- NEFL participates in Long-term potentiationProteinReactome R-HSA-9620244Inferred only
- NRG1 participates in Long-term potentiationProteinReactome R-HSA-9620244Inferred only
- NRGN participates in Long-term potentiationProteinReactome R-HSA-9620244Inferred only
- SRC participates in Long-term potentiationProteinReactome R-HSA-9620244Inferred only