Pathway
Initiation of Nuclear Envelope (NE) Reformation
Reassembly of the nuclear envelope (NE) is initiated at late anaphase/early telophase when BANF1 (BAF), which is dispersed throughout the cytoplasm during metaphase, accumulates on the surfaces of coalesced chromosomes. This is coordinated with the chromatin association of membranes and inner nuclear membrane proteins that include EMD (emerin), TMPO (LAP2beta), LEMD3 (MAN1) and LEMD2 (LEM2), and lamins (Haraguchi et al. 2008, reviewed by Wandke and Kutay 2013). The DNA-cross-bridging activity of BANF1 is required for individual chromosomes to properly coalesce for enclosure in a single nucleus.
REACT:R-HSA-2995383Reactome
What the reference databases state
Statements
16 statements
16 statements · 1 reference database · Subject: Initiation of Nuclear Envelope (NE) Reformation · Sources: Reactome
- ANKLE2 participates in Initiation of Nuclear Envelope (NE) ReformationProteinReactome R-HSA-2995383Inferred only
- BANF1 participates in Initiation of Nuclear Envelope (NE) ReformationProteinReactome R-HSA-2995383Inferred only
- CCNB1 participates in Initiation of Nuclear Envelope (NE) ReformationProteinReactome R-HSA-2995383Inferred only
- CCNB2 participates in Initiation of Nuclear Envelope (NE) ReformationProteinReactome R-HSA-2995383Inferred only
- CDK1 participates in Initiation of Nuclear Envelope (NE) ReformationProteinReactome R-HSA-2995383Inferred only
- EMD participates in Initiation of Nuclear Envelope (NE) ReformationProteinReactome R-HSA-2995383Inferred only
- KPNB1 participates in Initiation of Nuclear Envelope (NE) ReformationProteinReactome R-HSA-2995383Inferred only
- LBR participates in Initiation of Nuclear Envelope (NE) ReformationProteinReactome R-HSA-2995383Inferred only
- LEMD2 participates in Initiation of Nuclear Envelope (NE) ReformationProteinReactome R-HSA-2995383Inferred only
- LEMD3 participates in Initiation of Nuclear Envelope (NE) ReformationProteinReactome R-HSA-2995383Inferred only
- LMNB1 participates in Initiation of Nuclear Envelope (NE) ReformationProteinReactome R-HSA-2995383Inferred only
- PPP2CA participates in Initiation of Nuclear Envelope (NE) ReformationProteinReactome R-HSA-2995383Inferred only
Show the remaining 4
- PPP2R1A participates in Initiation of Nuclear Envelope (NE) ReformationProteinReactome R-HSA-2995383Inferred only
- PPP2R2A participates in Initiation of Nuclear Envelope (NE) ReformationProteinReactome R-HSA-2995383Inferred only
- SIRT2 participates in Initiation of Nuclear Envelope (NE) ReformationProteinReactome R-HSA-2995383Inferred only
- VRK1 participates in Initiation of Nuclear Envelope (NE) ReformationProteinReactome R-HSA-2995383Inferred only