Pathway
FTO obesity variant mechanism
Mechanism underlying the association of FTO locus variants and obesity. The wild type T allele at rs1421085 in the FTO locus comprises a protein-DNA binding motif for ARID5B that represses the tran...
WP:3407
What the reference databases state
Statements
8 statements
8 statements · 1 reference database · Subject: FTO obesity variant mechanism · Sources: WikiPathways
- ARID5B participates in FTO obesity variant mechanismProteinWikiPathways WP3407Inferred only
- FTO participates in FTO obesity variant mechanismProteinWikiPathways WP3407Inferred only
- IRX3 participates in FTO obesity variant mechanismProteinWikiPathways WP3407Inferred only
- IRX5 participates in FTO obesity variant mechanismProteinWikiPathways WP3407Inferred only
- PPARGC1A participates in FTO obesity variant mechanismProteinWikiPathways WP3407Inferred only
- PRDM16 participates in FTO obesity variant mechanismProteinWikiPathways WP3407Inferred only
- TBX1 participates in FTO obesity variant mechanismProteinWikiPathways WP3407Inferred only
- UCP1 participates in FTO obesity variant mechanismProteinWikiPathways WP3407Inferred only