Pathway
Formation of annular gap junctions
Gap junction plaque internalization and the disruption cell communication requires a reorganization of Cx molecular interactions. Proteins including Dab-2, AP-2, Dynamin and Myosin VI associate with gap junction plaques permitting the internalisation of plaques after clathrin association. Until now, two kinds of annular gap junctions have been described. The first is a small vesicle like structure which permits gap junction plaque renewal without arrest of functionality. The second is a large annular structure, composed primarily of the junctional plaques of two adjacent cells.
REACT:R-HSA-196025Reactome
What the reference databases state
Statements
11 statements
11 statements · 1 reference database · Subject: Formation of annular gap junctions · Sources: Reactome
- ACTB participates in Formation of annular gap junctionsProteinReactome R-HSA-196025Inferred only
- ACTG1 participates in Formation of annular gap junctionsProteinReactome R-HSA-196025Inferred only
- AP2M1 participates in Formation of annular gap junctionsProteinReactome R-HSA-196025Inferred only
- CLTA participates in Formation of annular gap junctionsProteinReactome R-HSA-196025Inferred only
- CLTB participates in Formation of annular gap junctionsProteinReactome R-HSA-196025Inferred only
- CLTC participates in Formation of annular gap junctionsProteinReactome R-HSA-196025Inferred only
- CLTCL1 participates in Formation of annular gap junctionsProteinReactome R-HSA-196025Inferred only
- DAB2 participates in Formation of annular gap junctionsProteinReactome R-HSA-196025Inferred only
- DNM1 participates in Formation of annular gap junctionsProteinReactome R-HSA-196025Inferred only
- DNM2 participates in Formation of annular gap junctionsProteinReactome R-HSA-196025Inferred only
- GJA1 participates in Formation of annular gap junctionsProteinReactome R-HSA-196025Inferred only