Pathway
Enzymatic degradation of dopamine by COMT
Dopamine once taken up by the dopamine transporter from the extracellular space into the cytosol is metabolized in a two step reaction to homovanillic acid.The first reaction is catalyzed by catecholamine o-methyl transferase and the subsequent reaction is catalyzed by monoamine oxidase A.
REACT:R-HSA-379397Reactome
What the reference databases state
Statements
3 statements
3 statements · 1 reference database · Subject: Enzymatic degradation of dopamine by COMT · Sources: Reactome
- COMT participates in Enzymatic degradation of dopamine by COMTProteinReactome R-HSA-379397Inferred only
- MAOA participates in Enzymatic degradation of dopamine by COMTProteinReactome R-HSA-379397Inferred only
- TOMT participates in Enzymatic degradation of dopamine by COMTProteinReactome R-HSA-379397Inferred only