Pathway
Classical Kir channels
Classical Kir channels are inwardly rectifying K+ channels with strong inwardly rectifying currents that contribute to highly negative resting membrane potential, prolonged action potential plateau and rapid repolarization in the final stage of action potential. Classical Kir channels are found in various cells such as cardiac myocytes, purkinje fibers, atrial and ventricular tissues. Rectification is caused by intracellular Mg2+ ions and polyamines.
REACT:R-HSA-1296053Reactome
What the reference databases state
Statements
4 statements
4 statements · 1 reference database · Subject: Classical Kir channels · Sources: Reactome
- KCNJ12 participates in Classical Kir channelsProteinReactome R-HSA-1296053Inferred only
- KCNJ14 participates in Classical Kir channelsProteinReactome R-HSA-1296053Inferred only
- KCNJ2 participates in Classical Kir channelsProteinReactome R-HSA-1296053Inferred only
- KCNJ4 participates in Classical Kir channelsProteinReactome R-HSA-1296053Inferred only