Endpoint
Urinary lactulose/mannitol ratio
CAT:outcome/urinary-lactulose-mannitol-ratioreported in ratio1 finding from 1 compound
What moved it
How to read these marks1 finding · 1 compound · by evidence strength
| Compound | Direction | Findings | Strongest evidence |
|---|---|---|---|
| L-glutamine | down | 1 | Evidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence. |
Reported to move it
1 finding
L-glutamine — decreases
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“The levels of diamine oxidase (DAO), lactulose/mannitol (L/M), β2-microglobulin, lactate dehydrogenase (LDH), hydroxybutyrate dehydrogenase (HBD) and cardiac troponin l (cTnl) in the B+G group were significantly lower than those in the B group (p < 0.05 or 0.01).”
Quoted verbatim from Glutamine relieves the hypermetabolic response and reduces organ damage in severe burn patients: A multicenter, randomized controlled clinical trial.. - Study
- RCT
- Population
- Adult burn patients with TBSA 30-70% (multicenter RCT); B+G (burn+glutamine) arm vs B (burn control) arm, measured on the 7th and/or 14th day after treatment (specific timepoint not stated for this comparison)
Glutamine relieves the hypermetabolic response and reduces organ damage in severe burn patients: A multicenter, randomized controlled clinical trial.2022PMID:34973853Permalink
How it is measured
Ratio of lactulose to mannitol recovered in urine following an oral dual-sugar challenge, quantified by HPLC or LC-MS. Collection window recorded with each finding — 5-hour and 24-hour collections index different intestinal regions.
Measured, not recorded
- Subject
- urinary lactulose/mannitol ratio
- Measurements
- 1 measurement
- Recorded as a finding
- No
Show what was measured
urinary lactulose/mannitol ratio
decreases
urinary lactulose/mannitol ratio (MD: -0.01; 95% CI -0.02 to -0.001; I2 = 29.8%)
PMID:38361147 · one of two readings recorded this
Sources cited
1 paper
- Subject
- urinary lactulose/mannitol ratio
- Findings
- 1
- Papers
- 1