Endpoint
Metabolic syndrome (presence)
A cluster of symptoms that are risk factors for cardiovascular diseases and type 2 diabetes mellitus. The major components of metabolic syndrome include abdominal obesity; atherogenic dyslipidemia; hypertension; hyperglycemia; insulin resistance; a proinflammatory state; and a prothrombotic (thrombosis) state.
CAT:outcome/metabolic-syndrome-presencereported in odds ratio2 findings from 1 compound
What moved it
How to read these marks2 findings · 1 compound · by evidence strength
| Compound | Direction | Findings | Strongest evidence |
|---|---|---|---|
| magnesium(2+) | down | 2 | Evidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers. |
Reported to move it
2 findings
magnesium(2+) — decreases
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Findingreplicated ×1“In the analysis of all of the studies, the overall RR demonstrated a statistically significant inverse association between dietary magnesium intake of an increase in 150 mg/day and metabolic syndrome (RR, 0.88; 95% CI, 0.84–0.93).”
Quoted verbatim from Dietary magnesium intake and metabolic syndrome in the adult population: dose-response meta-analysis and meta-regression.. - Study
- meta-analysis
- Population
- Adults in 10 observational studies (8 cross-sectional, 2 prospective cohort); dietary magnesium intake, per 150 mg/day increment
Effect 0.88 risk ratio, 95% CI 0.84 to 0.93
Dietary magnesium intake and metabolic syndrome in the adult population: dose-response meta-analysis and meta-regression.2014PMID:25533010Permalink
magnesium(2+) — decreases
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Findingreplicated ×1“As shown in, for the five cross-sectional studies that reported risk of having metabolic syndrome according to magnesium intake categories, the pooled estimate from the meta-analysis indicated an inverse association between dietary magnesium intake and the prevalence of metabolic syndrome.”
Quoted verbatim from Dietary magnesium intake and risk of metabolic syndrome: a meta-analysis.. - Study
- meta-analysis
- Population
- General adult populations (age >=18 years) in five pooled cross-sectional studies; highest versus lowest category of dietary magnesium intake estimated from food-frequency questionnaires, diet recalls or food records. Metabolic syndrome defined by NCEP/ATP III criteria. Not a supplementation trial.
Dietary magnesium intake and risk of metabolic syndrome: a meta-analysis.2014PMID:24975384Permalink
How it is measured
Presence of the metabolic syndrome by a stated diagnostic criteria set (ATP III, IDF, or the harmonised definition). The criteria set is recorded with each finding, since the definitions differ in waist thresholds and in how many criteria are required.
Sources cited
2 papers
- Subject
- metabolic syndrome (presence)
- Findings
- 2
- Papers
- 2