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Catalyst

CDP-cholineFinding

CDP-choline increases Mini-Mental State Examination total score

raisesVery limited evidenceFinding

01 · The sentence it was drawn from

“At 90 days, MMSE scores were higher in the citicoline group than in the placebo group (25.2 ± 2.1 vs. 21.5 ± 3.4; P < 0.001).”
Quoted verbatim from Effect of citicoline on cognitive function and functional recovery in patients with mild-to-moderate traumatic brain injury: a randomized placebo-controlled trial.
This finding among the 10 findings on its endpoint

CDP-choline

Mini-Mental State Examination total score

raises

Who
Adults with mild-to-moderate traumatic brain injury, single-centre triple-blind pilot trial; 90-day timepoint
Dose studied
1000 mg/day for 90 days

Very limited evidencePMID 42679920 · 2026

02 · The study

Study
RCT
Duration
3 months

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limitedthis finding
  • insufficient

03 · The paper

Neuroscience
What else it reported1 finding · 1 compound · 1 endpoint

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M70H6MP6CFBM4RVP00H7HZX9