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Catalyst

L-phenylalanineFinding

L-phenylalanine has no detected effect on ad libitum test-meal energy intake

no difference foundVery limited evidenceFinding

01 · The sentence it was drawn from

“L-phenylalanine reduced postprandial glucose area under the curve (AUC)70-150mins relative to placebo (P = .0317) but did not affect subjective appetite or energy intake (P > .05).”
Quoted verbatim from Differential effects of L- and D-phenylalanine on pancreatic and gastrointestinal hormone release in humans: A randomized crossover study.
This finding among the 9 findings on its endpoint

L-phenylalanine

Ad libitum test-meal energy intake

no difference found

Who
Eleven participants in an acute randomised double-blind placebo-controlled crossover study; energy intake at an ad libitum meal served 70 minutes after ingestion; L-phenylalanine arm against placebo (a D-phenylalanine arm is not part of this claim)
Dose studied
10 g L-phenylalanine, oral, single dose, ad libitum meal 70 minutes after ingestion

Very limited evidencePMID 32991046 · 2021

02 · The study

Study
crossover
Duration
1 day

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limitedthis finding
  • insufficient

03 · The paper

Diabetes, obesity & metabolism
What else it reported1 finding · 1 compound · 1 endpoint

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M70CSNN4BB3QN9D2MR25WSGV