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Catalyst

(R)-carnitineFinding

(R)-carnitine decreases glycated haemoglobin (HbA1c)

lowersVery limited evidenceFinding

01 · The sentence it was drawn from

“We found that every 1 g/d supplementation with l-carnitine significantly reduced body mass index (MD: -0.37 kg/m2, 95% CI: -0.59, -0.15; I2 =93%, n=13, GRADE=low), HbA1c (MD: -0.16%, 95% CI: -0.32, -0.01; I2 = 94%, n = 18, GRADE = moderate), and low-density lipoprotein cholesterol (MD: -0.11 mmol/L, 95% CI: -0.16, -0.05; I2 = 91%, n = 11, GRADE = high).”
Quoted verbatim from The Effects of L-Carnitine Supplementation on Weight Loss, Glycemic Control, and Cardiovascular Risk Factors in Patients With Type 2 Diabetes: A Systematic Review and Dose-response Meta-Analysis of Randomized Controlled Trials.
This finding among the 64 findings on its endpoint

(R)-carnitine

Glycated haemoglobin (HbA1c)

lowers

Effect as reported

−0.16mean difference

CI −0.32 to −0.01

Who
Adults with type 2 diabetes in 21 randomized trials (2041 patients); dose-response estimate per 1 g/d
Dose studied
per 1 g/d increment of l-carnitine (dose-response)

Very limited evidencePMID 38594107 · 2024

02 · The study

Study
meta-analysis
Duration
not reported

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limitedthis finding
  • insufficient

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M701EFQ92MGAQ1GKJRRJT707