(R)-carnitineFinding
(R)-carnitine decreases body mass index
lowersVery limited evidenceFindingreplicated ×2
01 · The sentence it was drawn from
“We found that every 1 g/d supplementation with l-carnitine significantly reduced body mass index (MD: -0.37 kg/m2, 95% CI: -0.59, -0.15; I2 =93%, n=13, GRADE=low), HbA1c (MD: -0.16%, 95% CI: -0.32, -0.01; I2 = 94%, n = 18, GRADE = moderate), and low-density lipoprotein cholesterol (MD: -0.11 mmol/L, 95% CI: -0.16, -0.05; I2 = 91%, n = 11, GRADE = high).”
(R)-carnitine
Body mass index
lowers
Effect as reported
−0.37mean difference
CI −0.59 to −0.15
- Who
- Adults with type 2 diabetes in 21 randomized trials (2041 patients); dose-response estimate per 1 g/d
- Dose studied
- per 1 g/d increment of l-carnitine (dose-response)
Very limited evidencePMID 38594107 · 2024
02 · The study
- Study
- meta-analysis
- Duration
- not reported
Evidence, by strength
- strong
- moderate
- limited
- very limitedthis finding
- insufficient
03 · The paper
Clinical therapeutics2024PMID 38594107doi 10.1016/j.clinthera.2024.03.002
04 · To cite this finding
This address does not changehttps://catalystproject.ai/e/01M701EFDZPYXJATCPCRY6XK6G