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Catalyst

(R)-carnitineFinding

(R)-carnitine decreases total cholesterol (TC)

lowersVery limited evidenceFindingreplicated ×1

01 · The sentence it was drawn from

“The pooled results indicated that L-carnitine administration led to a significant decrease in triglycerides (WMD: -10.35; 95% CI: -16.43, -4.27), total cholesterol (WMD: -9.47; 95% CI: - 13.23, -5.70) and LDL-cholesterol (LDL-C) concentrations (WMD: -6.25; 95% CI: -9.30, -3.21), and a significant increase in HDL-cholesterol (HDL-C) levels (WMD: 1.39; 95% CI: 0.21, 2.57).”
Quoted verbatim from The Effects of L-Carnitine Supplementation on Serum Lipids: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This finding among the 116 findings on its endpoint

(R)-carnitine

Total cholesterol (TC)

lowers

Effect as reported

−9.47mean difference

CI −13.23 to −5.7

Who
Patients and healthy individuals in 67 randomized controlled trials
Dose studied
not reported

Very limited evidencePMID 31470778 · 2019

02 · The study

Study
meta-analysis
Duration
not reported

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limitedthis finding
  • insufficient

03 · The paper

Current pharmaceutical design
What else it reported4 findings · 1 compound · 4 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M701EAXZVHN1PMPW1R0PTR0A