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Catalyst

cholineFinding

Choline has no detected effect on type 2 diabetes incidence

no difference foundVery limited evidenceFindingreplicated ×1

01 · The sentence it was drawn from

“There was no statistically significant association between every 1-SD increase in dietary choline and risk of type 2 diabetes (hazard ratio [HR] 1.01 [95% CI 0.87, 1.16]) nor between dietary betaine intake and the risk of type 2 diabetes (HR 1.01 [0.94, 1.10]).”
Quoted verbatim from The Association of Dietary Choline and Betaine With the Risk of Type 2 Diabetes: The Atherosclerosis Risk in Communities (ARIC) Study.
This finding among the 13 findings on its endpoint

choline

Type 2 diabetes incidence

no difference found

Effect as reported

1.01hazard ratio

CI 0.87 to 1.16

Who
Adults in the Atherosclerosis Risk in Communities study, free of diabetes at baseline; whole cohort, per 1-SD increase in dietary choline intake
Dose studied
dietary choline intake, per 1-SD increase

Very limited evidencePMID 32900787 · 2020

02 · The study

Study
cohort
Duration
not reported

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limitedthis finding
  • insufficient

03 · The paper

Diabetes care
What else it reported1 finding · 1 compound · 1 endpoint

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6ZWT888E6XZ1R622MYHWZNN