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Eleutherococcus senticosusFinding

Eleutherococcus senticosus decreases interleukin‑6 concentration

lowersVery limited evidenceFinding

01 · The sentence it was drawn from

“Compared with the LPS model group, ASTF significantly reduced the contents of IL-1β, IL-6, PGE2 and TNF-α in each dosage group (P<0.001), and except for the content of IL-1β, all of these effects were dose-dependent.”
Quoted verbatim from Acanthopanax senticosus total flavonoids alleviate lipopolysaccharide-induced intestinal inflammation and modulate the gut microbiota in mice.
This finding among the 81 findings on its endpoint

Eleutherococcus senticosus

Interleukin-6 concentration

lowers

Who
Male Kunming mice with intestinal inflammation induced by intraperitoneal LPS 10 mg/kg; serum IL-6 by ELISA after 7 days of treatment; all three ASTF dose groups (200, 400, 800 mg/kg) against the LPS model group
Dose studied
200, 400 or 800 mg/kg once daily by intragastric gavage for 7 days after the LPS injection

Very limited evidencePMID 35088071 · 2022

02 · The study

Study
animal · not in humans
Duration
7 days

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limitedthis finding
  • insufficient

03 · The paper

Bioscience reports
What else it reported2 findings · 0 compounds · 2 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6ZW96H6QP4EA5TX4AMMDN33