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malic acidFinding

Malic acid increases unstimulated whole salivary flow rate

raisesVery limited evidenceFinding

01 · The sentence it was drawn from

“A sialogogue spray containing 1% malic acid increased the unstimulated salivary flow rate in patients with type 2 diabetes mellitus suffering from xerostomia.”
Quoted verbatim from Effect of 1% malic acid spray on diabetes mellitus-induced xerostomia: A randomized clinical trial.
This finding among the 1 finding on its endpoint

malic acid

Unstimulated whole salivary flow rate

raises

Who
Patients with type 2 diabetes mellitus and xerostomia, randomised to 1% malic acid spray or placebo spray, assessed at 2 weeks follow-up
Dose studied
1% malic acid topical sialogogue spray, on demand for 2 weeks

Very limited evidencePMID 35913424 · 2024

02 · The study

Study
RCT
Duration
14 days

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limitedthis finding
  • insufficient

03 · The paper

Oral diseases
What else it reported1 finding · 1 compound · 1 endpoint

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6ZP55XZ939272340ZXB1REJ