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creatineFinding

Creatine is transported by SLC6A8

raisesVery limited evidenceFindingreplicated ×1

01 · The sentence it was drawn from

“The addition of extracellular creatine (1mM and 10mM) significantly increased intracellular creatine in control cells but not in CRT KD cells.”

Quoted verbatim from Creatine Transporter, Reduced in Colon Tissues From Patients With Inflammatory Bowel Diseases, Regulates Energy Balance in Intestinal Epithelial Cells, Epithelial Integrity, and Barrier Function.

This finding among the 2 findings on its endpoint

creatine

SLC6A8

is transported by

Who: T84 human intestinal epithelial cells, control versus lentiviral CRT (SLC6A8) knockdown
Dose studied: extracellular creatine 1 mM and 10 mM in culture media

Very limited evidencePMID 32433978 · 2020

02 · The study

Study: in vitro · not in humans
Duration: 4 days

Evidence, by strength

strong
moderate
limited
very limitedthis finding
insufficient

03 · The paper

Gastroenterology

Creatine Transporter, Reduced in Colon Tissues From Patients With Inflammatory Bowel Diseases, Regulates Energy Balance in Intestinal Epithelial Cells, Epithelial Integrity, and Barrier Function.

2020PMID 32433978doi 10.1053/j.gastro.2020.05.033

What else it reported1 finding · 1 compound · 1 endpoint

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6ZDAQG87PBPAYJEF6H4H7KN