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Catalyst

curcuminFinding

Curcumin increases HDL cholesterol

raisesLimited evidenceFindingreplicated ×2

01 · The sentence it was drawn from

“The updated MA showed that curcumin significantly increased HDL-c in overall patients, with an MD of 2.4 mg/dL (95% CI: 1.22, 3.57; I2 = 94%).”
Quoted verbatim from An Umbrella Review of Systematic Reviews and Meta-analyses of Randomized Controlled Trials Investigating the Effect of Curcumin Supplementation on Lipid Profiles.
This finding among the 93 findings on its endpoint

curcumin

HDL cholesterol

raises

Effect as reported

2.4mean difference

CI 1.22 to 3.57

Who
Adults in 72 randomised trials (87 arms) comparing curcumin supplementation with placebo or standard treatment, in healthy individuals and in patients with obesity, MAFLD, PCOS, metabolic syndrome, prediabetes or type 2 diabetes, ASCVD risk, CKD or dyslipidaemia; median follow-up 8 weeks
Dose studied
pooled across whole curcumin 500 to 3000 mg/day, curcumin extract 45 to 6000 mg/day and bioavailability-enhanced forms (including curcumin with piperine, nano-curcumin, phytosomal, micellar)

Limited evidencePMID 40044446 · 2025

02 · The study

Study
meta-analysis
Duration
not reported

Evidence, by strength

  • strong
  • moderate
  • limitedthis finding
  • very limited
  • insufficient

03 · The paper

Nutrition reviews
What else it reported1 finding · 1 compound · 1 endpoint

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6Y5Y5REN18X3BWQ8V7512QF