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Catalyst

coenzyme Q10Finding

Coenzyme Q10 has no detected effect on serum leptin

no difference foundLimited evidenceFinding

01 · The sentence it was drawn from

“The pooled estimates showed no significant effect of CoQ10 on adiponectin (WMD = 1.37 μg/mL; 95% CI: −0.35, 3.27; I 2 = 65.9 %; p = 0.032) or leptin (SMD = −0.32; 95% CI: −0.70, 0.06; I 2 = 0.0 %; p = 0.872), as both CIs crossed the null.”
Quoted verbatim from Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
This finding among the 24 findings on its endpoint

coenzyme Q10

Serum leptin

no difference found

Effect as reported

−0.32standardised mean difference

CI −0.7 to 0.06

Who
Adults with disorders of lipid and/or glucose metabolism, pooled randomized trials of CoQ10 alone or with co-interventions, against placebo, no treatment or the same co-intervention without CoQ10 (two RCTs)
Dose studied
60 to 600 mg/day, pooled

Limited evidencePMID 42192187 · 2026

02 · The study

Study
meta-analysis
Duration
not reported

Evidence, by strength

  • strong
  • moderate
  • limitedthis finding
  • very limited
  • insufficient

03 · The paper

Journal of diabetes research
What else it reported11 findings · 1 compound · 11 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6Y5K8QH4YYKZ0BRMS1XGS52